Due to various special physiological features and a genome that greatly
differs in structure, gene content and organization from other yeasts,
Y. lipolytica is widely used as a model organism. With its
characteristics, such as the ability to accumulate oil and the high
capacity for secretion of proteases and lipases, the yeast is also of
great interest for biotechnological applications.
The main topics covered in this Microbiology Monograph are:
comparative genomics; mitochondrial genomics and proteomics, including
the analysis of the respiratory chain; transposable elements and their
activities; non-coding RNA genes, which display a number of unusual and
remarkable features compared to other hemiascomycetes; utilization of
hydrophobic substrates, of n-alkane and its oxidized derivatives as
sources of carbon and energy; ambient pH signalling; comparison of
protein families in non-conventional yeasts and S. cerevisiae; and the
sulphur metabolism of cheese-ripening yeast.
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