The pregnant host is at risk for any of the viral diseases her
nonpregnant counterpart acquires. Additionally, pregnancy heightens our
concerns regarding specific viral diseases be- cause of their potential
for enhanced adverse effects on both maternal and fetal well-being. All
too often the obstetrician relinquishes responsibility for the
management of the gravida infected by a viral pathogen, and those expert
in infectious diseases are confounded by the influence of pregnancy on
these conditions. A major goal of this textbook is to narrow the gap
between the two aforementioned management dichotomies in the virally
infected pregnant woman. Weare at the infancy of our understanding of
viral infections in pregnancy. The current and anticipated advancements
are due in large part to a burgeoning oftechnological achievements in
the areas of immunodiagnostics, molecular biology, and
pharmacotherapeutics. Our in utero diagnostic capabilities, both
invasive and noninvasive, have also allowed us new opportunities to
study the effects of various maternal infectious disease processes on
the developing fetus. New insights have been recognized pertaining to
the maternal-fetal interface, the placenta, in that this structure is
now acknowledged to function as both a mechanical and an immunological
barrier to vertical transmission of infection. These observations
suggest that there will be an outpouring of new data in the next several
years that clinicians will need to master to maintain an appropriate
level of expertise in the care of their patients.