This volume contains the proceedings of an International Sympo- sium on
the Biology and Pharmacology of Tumor Cell Differentiation- held on June
29-July I, 1986 at the University of Tromso, Norway. The objective of
this meeting was to bring together scientists from various disciplines
to discuss recent advances in the understanding of tumor cell
differentiation and to bridge the gap between experimental findings and
clinical application of new knowledge. Thus the infor- mation will be of
value not only to basic scientists involved in mol- ecular and cell
biology, but also to pharmacologists and clinicians trying to develop
the concept of tumor cell differentiation as a thera- peutic modality.
Each plenary speaker and selected poster presenters were requested to
submit a comprehensive, up-to-date review of recent contributions to
their disciplines related to differentiation and: hematopoietic factors
and leukemic cells in culture vitamin deriva- tives and polyamines;
nucleosides and methylation; and cell interac- tions.