This textbook provides an authoritative introduction to both classical
and coalescent approaches to population genetics. Written for graduate
students and advanced undergraduates by one of the world's leading
authorities in the field, the book focuses on the theoretical background
of population genetics, while emphasizing the close interplay between
theory and empiricism. Traditional topics such as genetic and phenotypic
variation, mutation, migration, and linkage are covered and advanced by
contemporary coalescent theory, which describes the genealogy of genes
in a population, ultimately connecting them to a single common ancestor.
Effects of selection, particularly genomic effects, are discussed with
reference to molecular genetic variation. The book is designed for
students of population genetics, bioinformatics, evolutionary biology,
molecular evolution, and theoretical biology--as well as biologists,
molecular biologists, breeders, biomathematicians, and biostatisticians.
- Contains up-to-date treatment of key areas in classical and modern
theoretical population genetics
- Provides in-depth coverage of coalescent theory
- Discusses genomic effects of selection
- Gives examples from empirical population genetics
- Incorporates figures, diagrams, and boxed features throughout
- Includes end-of-chapter exercises
- Speaks to a wide range of students in biology, bioinformatics, and
biostatistics