Many of the most effective treatments for disease have been discovered
empir- ically. Nowadays, however, we think that understanding the
biology of a disease will lead us to design better treatments, and to
improve the application of treatments we already have. To accomplish
this, vast sums are expended on cancer research. Even so, to the casual
observer of clinical oncology the proliferation of studies and trials of
ever-different combinations of therapies looks like empiricism, at the
best. In the first part of this book, we have asked practising
clinicians in different specialities to assess the contributions of
biology and of empiricism to current approaches to treatment. In the
second part, we have asked researchers in different areas of biology
applied to cancer to assess the present and likely future impact of
their type of biology on cancer treatment and control. IX 1 Surgery
M.BAUM OBJECTIVES OF CANCER TREATMENT The objectives of cancer treatment
can be defined according to population requirements or according to the
needs of the individual. As far as the population is concerned,
Government authorities are entitled to expect that cancer treatment will
lead to mortality reductions and cost containment.