Because of the dearth of experimental animal models of psychiatric
disorders, the study of the effect of the disease state is only possible
in tissue derived from patients vs. controls, especially in the target
tissue of disease-related changes in the brain. The human postmortem
brain offers the most appropriate experimental paradigm towards
understanding the etiology of psychiatric disorders. The availability of
post-mortem human samples from psychiatric patients and comparison
groups in recent years has contributed prominently to the accumulating
body of information leading to a better understanding of these
disorders.
This is the first book to summarize this research approach and the
meaningful data which has recently been acquired.