Günter Siegl

(Author)

The Parvoviruses (Softcover Reprint of the Original 1st 1976)Paperback - Softcover Reprint of the Original 1st 1976, 19 January 2012

The Parvoviruses (Softcover Reprint of the Original 1st 1976)
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Part of Series
Virology Monographs Die Virusforschung in Einzeldarstellunge
Print Length
112 pages
Language
English
Publisher
Springer
Date Published
19 Jan 2012
ISBN-10
3709184320
ISBN-13
9783709184325

Description

I. Introduction Parvoviruses belong to the large group of viral agents of which virologists have become aware by chance in many biological materials due to the availabil- ity of more sensitive isolation techniques and the extensive use of the electron microscope. In general, many of these viruses lacked the stimulating background of an infectious disease and, therefore, have fallen into oblivion already soon after discovery. In case of parvoviruses, however, interest has been maintained because of the circumstances under which most of them were isolated. A great number of parvoviruses has been recovered from tissues of tumor- bearing animals, from cell-free filtrates of tumors, or from stable cell lines of tumor origin. These observations necessarily suggested the newly isolated viral agents of playing an important, yet unknown role in the induction and develop- ment of cancer. On the other hand, further parvoviruses were found constantly associated with adenoviruses. It was the experimental analysis of the multiplica- tion behaviour which then revealed that the association between parvoviruses and tumors or parvoviruses and adenoviruses originates from the basis of a cer- tain genetic defectiveness. For some members of the group this may be overcome by cellular helper effects in rapidly growing tissues, for several others, however, by biochemical events in the simultaneously occurring replication of an adeno- virus only. Additional points of view in favour of parvovirus research have arisen from experimental animal studies.

Product Details

Author:
Günter Siegl
Book Edition:
Softcover Reprint of the Original 1st 1976
Book Format:
Paperback
Country of Origin:
NL
Date Published:
19 January 2012
Dimensions:
24.41 x 16.99 x 0.64 cm
ISBN-10:
3709184320
ISBN-13:
9783709184325
Language:
English
Location:
Vienna
Pages:
112
Publisher:
Weight:
204.12 gm

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