The means by which proteins and RNAs are exchanged between cytoplasm and
nucleus have interested cell biologists for many years, and the field
has seen a number of exciting recent advances. Much has been learned
about the intricate architecture of the nuclear pore-complex, the
mechanisms by which transport substrates are sorted, and the supply of
energy for exchange processes. This book attempts a general review of
the growing body of knowledge. However, the authors challenge the
presumptions implicit in some interpretations of the evidence,
re-examining the concept of "transport" within cells, and suggesting
that lessons learned from nucleocytoplasmic transport studies can
elucidate wider aspects of cell biology.