This book is about the phenotypic and functional features of epidermal
Langerhans cells in experimental models and in clinical medicine.
Langerhans cells, members of the dendritic cell system in the skin, are
critically involved in the regulation of cell-mediated immune responses
and gain increasing attention in a wide spectrum of clinical areas such
as allergy, autoimmunity, transplantation and resistance to tumors and
infections. The book covers the latest, most timely developments in this
rapidly advancing field. Leading researchers describe functional
analyses at the cell and molecular level, elucidating processes related
to antigen presentation and the role of cytokines, and discuss
perspectives for a future use of Langerhans cells and other dendritic
cells in the immunotherapy of various diseases.