Nan M Laird

(Author)

The Fundamentals of Modern Statistical Genetics (2011)Paperback - 2011, 28 January 2013

The Fundamentals of Modern Statistical Genetics (2011)
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Part of Series
Statistics for Biology and Health
Print Length
226 pages
Language
English
Publisher
Springer
Date Published
28 Jan 2013
ISBN-10
1461427754
ISBN-13
9781461427759

Description

This book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. Starting with Mendel's first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. All commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. Numerous examples illustrate key points throughout the text, both of Mendelian and complex genetic disorders. The intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. A background in intermediate level statistical methods is required. The authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. No background in genetics is assumed.

Product Details

Authors:
Nan M LairdChristoph Lange
Book Edition:
2011
Book Format:
Paperback
Country of Origin:
NL
Date Published:
28 January 2013
Dimensions:
23.39 x 15.6 x 1.3 cm
ISBN-10:
1461427754
ISBN-13:
9781461427759
Language:
English
Location:
New York, NY
Pages:
226
Publisher:
Weight:
340.19 gm

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