The term cytoskeleton has become firmly established in today's
scientific vocabulary. Indeed, it is difficult to believe that only ten
years ago, it was virtually non-existent. Since then, the modern field
of research on the structural organization of the cytoplasm has turned
into one of the most productive and rapidly expanding research areas in
Cell Biology today. Considerable progress has been made towards the
identification of the various structural components of the cytoskeleton
and their interactions with one another and with membranes. The first
attempts to understand, in molecular terms, complex cellular processes
such as shape changes, locomotion, division, and organelle movements
have been made. And it is now apparent that the cytoskeleton has impact
on other biological processes such as the control of gene expression,
protein synthesis, cell cycle regulation, and development. This
monograph outlines the basic properties of the major components of the
polymeric filament networks and their interactions and associations.
Wherever possible, emphasis is placed on more recent references. Any
attempt to cover a research field this complex in an introductory mono-
graph is, by necessity, fragmentary, and oversights or omissions are
inevitable. I wish to apologize in advance to all those colleagues who
feel that their work is not adequately represented.