Walter Isaacson's #1 New York Times bestselling history of our
third scientific revolution: CRISPR, gene editing, and the quest to
understand the code of life itself, is now adapted for young readers!
When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home
from school one afternoon and found a book on her bed. It was The
Double Helix, James Watson's account of how he and Francis Crick had
discovered the structure of DNA, the spiral-staircase molecule that
carries the genetic instruction code for all forms of life.
This book guided Jennifer Doudna to focus her studies not on DNA, but on
what seemed to take a backseat in biochemistry: figuring out the
structure of RNA, a closely related molecule that enables the genetic
instructions coded in DNA to express themselves. Doudna became an expert
in determining the shapes and structures of these RNA molecules--an
expertise that led her to develop a revolutionary new technique that
could edit human genes.
Today gene-editing technologies such as CRISPR are already being used to
eliminate simple genetic defects that cause disorders such as Tay-Sachs
and sickle cell anemia. For now, however, Jennifer and her team are
being deployed against our most immediate threat--the coronavirus--and
you have just been given a front row seat to that race.