Alcoholism is a uniquely human condition. Although some forms of alcohol
dependence can be induced experimentally in a variety of laboratory
animals, the complete spectrum of alcoholism with all of its physical,
psychological, and social implications occurs only in man. The special
quality of this relationship becomes more significant when one considers
that the manifestations of most physical disease syndromes in animals
and man are more similar than they are different. The uniqueness of
alcoholism lies in the fact that it is one of the few physical diseases
which reflects at all levels the problems of individuals coping with the
complexities of human society. In order to present a more coherent
picture of these complex relationships, we have attempted to impose a
logical sequence upon the material. This sequence lies along a dual
parameter-from the physical to the social and from the theor- etical to
the empirical. Consequently, it was natural for the first volume in this
series to deal with biochemistry, the most basic and physical aspect of
the inter- action of alcohol and man. It is equally natural for this,
the second volume, to deal with physiology and behavior, for these
levels of phenomenology-partic- ularly the latter-are already more
empirical and psychological in their mani- festations. Finally, the
third volume, clinical pathology, describes the disease itself, with all
of the medical and social implications carried in the word "alcoholism.