The pandemic of 1918-20-commonly known as the Spanish flu-infected over
a quarter of the world's population and killed over fifty million
people. It is by far the greatest humanitarian disaster caused by an
infectious disease in modern history. Epidemiologists and health
scientists often draw on this experience to set the plausible upper
bound (the 'worst case scenario') on future pandemic mortality. The
purpose of this study is to piece together and analyse the scattered
multi-disciplinary literature on the pandemic in order to place debates
on the evolving course of the current COVID-19 crisis in historical
perspective. The analysis focuses on the changing characteristics of
pathogens and disease over time, the institutional factors that shaped
the global spread, the demographic and socio-economic consequences, and
pharmaceutical and non-pharmaceutical responses to the pandemic. This
title is also available as Open Access on Cambridge Core.