The first book to focus on comprehensive systems biology as applied to
drug discovery and development
Drawing on real-life examples, Systems Biology in Drug Discovery and
Development presents practical applications of systems biology to the
multiple phases of drug discovery and development. This book explains
how the integration of knowledge from multiple sources, and the models
that best represent that integration, inform the drug research processes
that are most relevant to the pharmaceutical and biotechnology
industries.
The first book to focus on comprehensive systems biology and its
applications in drug discovery and development, it offers comprehensive
and multidisciplinary coverage of all phases of discovery and design,
including target identification and validation, lead identification and
optimization, and clinical trial design and execution, as well as the
complementary systems approaches that make these processes more
efficient. It also provides models for applying systems biology to
pharmacokinetics, pharmacodynamics, and candidate biomarker
identification.
Introducing and explaining key methods and technical approaches to the
use of comprehensive systems biology on drug development, the book
addresses the challenges currently facing the pharmaceutical industry.
As a result, it is essential reading for pharmaceutical and biotech
scientists, pharmacologists, computational modelers, bioinformaticians,
and graduate students in systems biology, pharmaceutical science, and
other related fields.