The patient with sepsis provides a major challenge to the hospital acute
team and septic shock is the commonest cause of admission to General
Critical Care Units in the industrialized world. The incidence of sepsis
is also increasing, in part due to the more complex patient case mix
which is a feature of modern hospital practice. Sepsis is a
multi-factorial disease process and this volume provides comprehensive
and in-depth reviews of both the basic science and more practical
aspects of patient management. Coverage includes detailed information on
the epidemiology and genetics of sepsis as well as the metabolic and
cardiovascular responses to infection.
The book also reviews infectious disease in relation to sepsis,
haematological aspects of sepsis, as well as the currently controversial
areas of clinical trial design in sepsis and protocol-driven care. In
addition, a specific chapter, with illustrated cases, draws practical
lessons and offers useful management tips.