The revitalization approach for managing immature permanent teeth with
infected pulp and/or apical periodontitis allows the ingrowth of vital
tissue consisting of tissues resembling cementum, PDL, bone. These
tissues are not pulp tissues. They do not function like pulp tissue.
Therefore revitalization is better termed as wound repair. Pulp tissue
may survive infection, recover, and remain healthy. The clinical case
reports have shown narrowing of canal and root lengthening however.
Although revitalization procedure is more favorable than the traditional
apexification procedures in terms of having vital tissues including
cementum like deposited on canal walls, the long term outcome of these
new tissues in the canal space needs further investigation. The
available case reports of pulp revascularization were generally reported
on young patients (with high stem cell populations) and teeth with open
apices. However, for regenerative endodontic procedures to be widely
available and predictable, Endodontists will have to depend on tissue
engineering therapies to regenerate pulp dentin tissue.