Renal Fibrosis: Mechanisms and Therapies (2019)Hardcover - 2019, 24 August 2019

Renal Fibrosis: Mechanisms and Therapies (2019)
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Part of Series
Advances in Experimental Medicine and Biology
Print Length
709 pages
Language
English
Publisher
Springer
Date Published
24 Aug 2019
ISBN-10
9811388709
ISBN-13
9789811388705

Description

This book systemically presents the latest research on renal fibrosis, covering all the major topics in the field, including the possible mechanisms, biomarkers, and strategies for prevention and treatment of chronic kidney disease (CKD). Due to its high prevalence, CKD represents a huge global economic and social burden. Irrespective of the initial causes, CKD progresses to end stage kidney disease (ESKD) due to renal fibrosis, which is characterized by glomerulosclerosis, tubule atrophy and atresia, and the excessive accumulation of extracellular matrix (ECM) in the kidney. Unfortunately, an estimated 1%-2% of the adult population living with CKD will need renal replacement therapy at some point as a result of ESKD. As such, strategies for preventing or slowing CKD progression to ESKD are of utmost importance, and studies aiming to understand the mechanisms of renal fibrosis have been the focus of intensive research. Recently, novel insights into the pathophysiological processes have furthered our understanding of the pathogenesis of renal fibrosis, and more importantly, promoted studies on the early diagnosis and treatment of CKD. This book draws lessons from the extensive, state-of-the-art research in this field, elaborating the new theories and new techniques to offer readers a detailed and comprehensive understanding of renal fibrosis and as well as inspiration for future research directions.

Product Details

Book Edition:
2019
Book Format:
Hardcover
Country of Origin:
NL
Date Published:
24 August 2019
Dimensions:
23.39 x 15.6 x 3.96 cm
ISBN-10:
9811388709
ISBN-13:
9789811388705
Language:
English
Location:
Singapore
Pages:
709
Publisher:
Springer
Weight:
1188.41 gm

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