Qualitative evaluations of buccal smear specimens have indicated an
unusually high incidence of triple-X females in a hospitalized schizo-
phrenic population. Specimens from adult prisoners have also indicated
an unusually high incidence of triple-X females. Studies of a population
of confined juvenile offenders, on the other hand, have indicated an
unusually high incidence of one-X females. No unusual indications were
observed in a population of "normal" volunteer females. The data and
their implications are discussed in context with previous observations.
ACKNOWLEDGMENTS This study was made possible primarily by research
grants from the Scottish Rite Committee on Research in Schizophrenia,
The National Association for Mental Health, Inc. Additional support was
provided by a grant from the National Institutes of Health, GRS-05563.
The study has been supported by the State of Ohio, Department of Mental
Hygiene and Correction, Division of Mental Hygiene. The author is
particularly indebted to Edward N. Hinko, M.D., Regional Director of
Research, whose advice and help made the present study possible.
Invaluable cooperation and help have been received from the following
administrators and their staffs: F. A. Lingl, M.D. (Cleve- land
Psychiatric Institute); Martha Wheeler (Ohio Reformatory for Women); M.
B. McLane (Scioto Village); M. B. Holmes, M. D., and S. Caruso, M. D.
(Massillon State Hospital); G. F. Ogram, M. D. (Athens State Hospital);
C. Waltner, M. D. (Woodside Receiving Hospital); A. Mako, M. D.
(Fairhill Psychiatric Hospital); and W. G. Stover, M. D.