All epidemiological data predict an endemic rise of prostate cancer in
populations with a high proportion of elderly people, leading to a major
health problem. The only way to stem this evolution is early detection
in organised random- ised trials. Discussion of this controversial
subject is followed by an exhaustive review of the endocrine mechanisms
stimulating prostate growth and the promising avenues of future research
and treatment. Radical prostatectomy and radiotherapy are presented and
analysed. Once patients are past this stage of cure, a wide array of
medical treatments are available. Endocrine treatment is the first
choice, and the different regimes are reviewed as to their respective
advantages and side effects. An entirely new approach to hormone
refractory diseases completes this overview.