I first became interested in prolactin a little over two years ago. I
was then working in Nairobi and I knew nothing about the hormone apart
from its role in lactation. Professor Mohammed Hyder of the Department
of Zoology in the University of Nairobi was interested in the endocrine
mechanisms which enable Tilapia fish to adapt to water with a very high
electrolyte content. He invited me to a seminar given by Professor
Howard Bern which was largely concerned with the role prolactin plays in
fluid and electrolyte balance in sub-mammalian vertebrates. This
inspired me to begin a programme of research into the roles prolactin
plays in man and other animals. Very few physiologists or clinicians
seem aware of the multifarious effects of prolactin in mammals. This
book therefore aims to give a comprehensive account of the mammalian
physiology of prolactin and to make suggestions about its possible role
in diseases ranging from cancer to mental illness. The two subjects
which have been previously widely covered, the roles of prolactin in
lactation and in rat mammary cancer, are presented relatively briefly
though with a full list of references. Other subjects are dealt with
more extenSively and I hope that many research workers and clinicians
may find the book helpful.