The first contribution reviews the occurrence of xanthine alkaloids in
the plant kingdom and the elucidation of the caffeine biosynthesis
pathway, providing details of the N-methyltransferases, belonging to the
motif B' methyltransferase family which catalyze three steps in the four
step pathway leading from xanthosine to caffeine. The second
contribution in this book provides a background on the molecule and
related compounds and update knowledge on the most recent advances in
Iboga alkaloids. The third contribution presents a comprehensive
analysis of frequently occurring errors with respect to 13C NMR
spectroscopic data and proposes a straightforward protocol to eliminate
a high percentage of the most obvious errors.