Although monotherapy is generally recommended as the treatment of
choice, treatment resistance of patients with psychosis, cognitive, mood
and anxiety disorders represents a significant clinical problem. In this
context, augmentation and combination strategies are commonly employed
to address this problem. Although multiple medication use common in
psychiatric practice, reasons, efficacy and safety for polypharmacy, and
augmentative strategies have remained unclear. It remains unclear if
there is an evidence base to support polypharmacy. Furthermore,
excessive and inappropriate use of psychotropic medications has been
recognized as a public health problem. This volume is the first
comprehensive, clinically oriented, reference on the multiple medication
use to treat psychotic, cognitive, mood and anxiety disorders.