This volume is based on a very successful meeting on organ
transplantation that was held in Kuwait in 1990 under the auspices of
the Middle East Society for Organ Transplantation. An international
group of organ transplant experts attended this conference and their
contributions and deliberations have been recent1y updated to produce
this definitive and authoritative summary of current clinic al practice
in organ transplantation. The initial chapters appropriately focus on
the immunology of organ trans- plantation with special emphasis on the
initial events in the induction of alloreactivity, the mechanisms of
rejection, and the potential for tolerance induction. A strong emphasis
is placed on the diagnosis of rejection by cellular analysis. The
section on immunosuppression deals with several new areas of clinical
therapy. The section on renal transplantation is unique in several
respects, the long-term results from various countries, including the
Middle East, are summarized, the use of living unrelated donors and of
ABO incom- patible donors - all strategies to maximize organ
availability - are presented.