Epistemology, as generally understood by philosophers of science, is
rather remote from the history of science and from historical concerns
in general. Rheinberger shows that, from the late nineteenth through the
late twentieth century, a parallel, alternative discourse sought to come
to terms with the rather fundamental experience of the thoroughgoing
scientific changes brought on by the revolution in physics. Philosophers
of science and historians of science alike contributed their share to
what this essay describes as an ongoing quest to historicize
epistemology. Historical epistemology, in this sense, is not so
concerned with the knowing subject and its mental capacities. Rather, it
envisages science as an ongoing cultural endeavor and tries to assess
the conditions under which the sciences in all their diversity take
shape and change over time.