Occult atherosclerotic diseases impose great challenges in the
cardiovascular practice. Although their pathology is not much different
from that of the overt group of diseases, the clinical approach to their
diagnoses remains a puzzle. This has mainly emerged as a result of the
problems faced in trying to pick up the vulnerable subjects from among
the general public. More definitive candidates to be evaluated are those
belonging to one of the high risk groups. There are no statistical
figures available on the incidence of occult atherosclerotic disease in
the "non risky" general public and this is definitely an area that needs
further investigation. Atherosclerotic disease whether they are in the
cerebral, coronary, renal or lower limb arteries are theoretically
interrelated because the basic patho- logical changes are usually
similar. However there still remain some differ- ences which are mainly
due to variation in the flow pattern in the arteries. Thus it will be
important clinically and from the management point of view to
investigate for the presence of occult disease in other arteries if an
atherosclerotic disease in a certain artery has been discovered. This
approach is of a great significance especially from the preventive point
of view in order to avoid catastrophic events which may have resulted
from pathology in the other region.