Forty (40) age matched individuals of male and female, young and old
were selected as normal and obese on the basis of their body mass index
(BMI). A significant increase in concentration of serum glucose,
cholesterol, triglyceride, LDL, albumin, ALT, AST, total oxidant status,
MDA and Hcy and a significant decrease in concentration of HDL, total
proteins, globulins and antioxidant status (AOS) were observed in obese
as compared to normal individuals. Sodium, potassium, magnesium and
manganese concentration were significantly high and calcium, CU, Zn and
Fe concentration did decrease significantly in obese individuals. Serum
globulin, total antioxidant status and iron concentration were negative
while body mass index, systolic blood pressure, glucose, cholesterol,
triglyceride, LDL, albumin, ALT, total oxidants status, MDA, sodium and
manganese did show a positive correlation with Hcy in obese individuals.
DNA damage was positively correlated with BMI, systolic blood pressure,
cholesterol, triglycerides, LDL, albumin, ALT, total oxidant status,
MDA, sodium, potassium and magnesium while negative correlation was
observed with globulin, AOS and iron contents
