need for an interdisciplinary approach to research, although
scientifically desirable and laudable, is not easily met by the
individual investigator, a statement which I must now qualify lest it be
taken as a faint-hearted view of the problems which confront us in this
or any other field of disease-orientated re- search. In recent years the
growth and scope of MS research parallels, in fact reflects, that which
has occurred more generally concern- ing research at all levels of
complexity into the nature and modes of operation of the nervous systems
of different animals. With respect to these developments Cowan (2) has
observed that "this has led to the gradual emergence of a new,
interdisciplinary ap- proach to the study of the nervous system which
has come to be known as Neuroscience. " At the center of neuroscience
stands man striving to comprehend hirnself, not only in terms of the
nuts and bolts of his own ner- vous system and that of lower animals,
but perhaps preoccupied most of all with the higher level nervous
functions of perception, volition, cognition, and mentation, which
characterize his "self. " The investigation of these processes depends
ultimately on re- search on man hirnself and the analysis of these
processes in depth often must wait on Nature's own experiments to
provide, through disease, the chance anatomical or biochemical lesions
which dissect human behavior and expose the residual functions for
scientific study.