Mycobacterium Tuberculosis: Interactions with the Immune System (Softcover Reprint of the Original 1st 1988)Paperback - Softcover Reprint of the Original 1st 1988, 29 March 2012

Mycobacterium Tuberculosis: Interactions with the Immune System (Softcover Reprint of the Original 1st 1988)
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Part of Series
Infectious Agents and Pathogenesis
Print Length
448 pages
Language
English
Publisher
Springer
Date Published
29 Mar 2012
ISBN-10
146845420X
ISBN-13
9781468454208

Description

Tuberculosis once again occupies a special position in the areas of infec- tious diseases and microbiology. This disease has been important to mankind since even before biblical times. Tuberculosis has been a major cause of morbidity and mortality in humans, especially in highly ur- banized Europe, until a few decades ago. Indeed, this disease became a center of many novels, plays, and operas, since it appeared to be quite popular to have the heroine dying of "consumption. " Most importantly, tuberculosis also became the focus of attention for many investigations during the 19th and even the 20th centuries. Major advances were made in the areas of isolation and identification of M. tuberculosis and related microorganisms. The discovery, by Robert Koch, that tuberculosis was caused by an infectious agent revolutionized our thinking about dis- eases. Koch's postulates were developed with tuberculosis in mind and became a focal point for many advances in microbiology and medicine. Studies with mycobacteria as a central focus have also led to revolu- tionary new concepts about immunology in general. Koch himself showed that those exposed to M. tuberculosis develop a skin hypersen- sitivity or allergy to the microorganism's antigens, an observation which was the starting point for many important developments. Indeed, imme- diate-type hypersensitivity and atopic or IgE-mediated allergy were de- fined in relation to the delayed-type cutaneous hypersensitivity evi- denced with the tubercle bacillus.

Product Details

Book Edition:
Softcover Reprint of the Original 1st 1988
Book Format:
Paperback
Country of Origin:
NL
Date Published:
29 March 2012
Dimensions:
22.86 x 15.24 x 2.31 cm
Genre:
Ecology
ISBN-10:
146845420X
ISBN-13:
9781468454208
Language:
English
Location:
New York, NY
Pages:
448
Publisher:
Springer
Weight:
598.74 gm

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