This book discusses the ways in which mathematical, computational, and
modelling methods can be used to help understand the dynamics of
intracellular calcium. The concentration of free intracellular calcium
is vital for controlling a wide range of cellular processes, and is thus
of great physiological importance. However, because of the complex ways
in which the calcium concentration varies, it is also of great
mathematical interest.This book presents the general modelling theory as
well as a large number of specific case examples, to show how
mathematical modelling can interact with experimental approaches, in an
interdisciplinary and multifaceted approach to the study of an important
physiological control mechanism.
Geneviève Dupont is FNRS Research Director at the Unit of
Theoretical Chronobiology of the Université Libre de Bruxelles; Martin
Falcke is head of the Mathematical Cell Physiology group at the Max
Delbrück Center for Molecular Medicine, Berlin; Vivien Kirk is an
Associate Professor in the Department of Mathematics at the University
of Auckland, New Zealand; James Sneyd is a Professor in the Department
of Mathematics at The University of Auckland, New Zealand.