Increasing interest in mitochondrial bioenergetics is being driven by
the impact of drug and environmental chemical-induced disturbances of
mitochondrial function as well as hereditary deficiencies and the
progressive deterioration of bioenergetic performance with age. These
initiatives have fostered the investigation of genetic and environmental
influences on bioenergetics. In Mitochondrial Bioenergetics: Methods
and Protocols, researchers in the field detail the practical principles
and assays designed to derive quantitative assessment of each set of
parameters that reflect different aspects of mitochondrial
bioenergetics. Written in the highly successful Methods in Molecular
Biology(TM) series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and key tips on
troubleshooting and avoiding known pitfalls
Authoritative and practical, Mitochondrial Bioenergetics: Methods and
Protocols helps elevate the quality and rate of investigative
discoveries regarding disease states associated with environmental or
genetic influences on mitochondrial bioenergetics.