- __ - ___ __ - - __ e _e __ M-A-S-S
S-P-£-C-T-R-O-M-£-T-R-Y in Morse code This volume collects descriptions
of selected recent developments in state-of- the-art mass spectrometric
methods and reflects the broad-based approaches that mass
spectroscopists apply to a variety of important clinical and bio-
medical problems. One chapter reviews current mass-spectrometric
instrumen- tation and techniques, and other chapters describe the use of
mass-spectro- metric methods for the analysis of
diacylglycerylphospholipids; modifications to DNA molecules; the
characterization of variant hemoglobins; and charac- terization of
urinary nucleosides. The final chapter describes the new technique of
combined microdialysis/mass spectrometry. This volume represents the
collected efforts of several highly productive researchers who have
developed new methods and instrumentation and have applied them to
current research problems, such as lipid storage diseases, cancer,
hemoglobinopathies, and brain neurochemistry. The chapters in Vol- umes
1 and 2 define the outlines of clinical and biomedical mass spectrometry
and attest to the flexibility and creativity of mass spectroscopists and
their interaction with biologic and clinical scientists. The authors in
this volume are to be congratulated for their writing efforts, their
scientific vigor and rigor, their intellectual contributions, and the
ex- perimental details that are described in these chapters. I thank
each author for collaborating with me on the production of this volume,
and I hope these chapters will help the practitioners of, and the
newcomers to, the field of mass spectrometry.
