During the past decade a significant international research effort has
been directed towards understanding the composition and regulation of
the preocular tear film. This effort has been motivated by the
recognition that the tear film plays an essential role in maintaining
corneal and conjunctival integrity, protecting against microbial
challenge and preserving visual acuity. In addition, research has been
stimulated by the knowledge that alteration or deficiency of the tear
film, which occurs in countless individuals throughout the world, may
lead to desiccation of the ocular surface, ulceration and perforation of
the cornea, an increased incidence of infectious disease, and
potentially, pronounced visual disability and blindness. 7 To promote
further progress in this field of vision research, the International
Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic
Science and Clinical Relevance was held in the Southampton Princess
Resort in Bermuda from November 14 to 17, 1992. This meeting was
designed to assess critically the current knowledge and 'state of the
art' research on the structure and function of lacrimal tissue and tears
in both health and disease. The goal of this conference was to provide
an international exchange of information that would be of value to basic
scientists involved in eye research, to physicians in the
ophthalmological community, and to pharmaceutical companies with an
interest in the treatment of lacrimal gland, tear film or ocular surface
disorders (e. g. Sjogren's syndrome).