In longitudinal studies it is often of interest to investigate how a
marker that is repeatedly measured in time is associated with a time to
an event of interest, e.g., prostate cancer studies where longitudinal
PSA level measurements are collected in conjunction with the
time-to-recurrence. Joint Models for Longitudinal and Time-to-Event
Data: With Applications in R provides a full treatment of random
effects joint models for longitudinal and time-to-event outcomes that
can be utilized to analyze such data. The content is primarily
explanatory, focusing on applications of joint modeling, but sufficient
mathematical details are provided to facilitate understanding of the key
features of these models.
All illustrations put forward can be implemented in the R programming
language via the freely available package JM written by the author. All
the R code used in the book is available at:
http: //jmr.r-forge.r-project.org