It is a great pleasure for me to contribute a brief introduction to this
volume, to which so many of my colleagues at Groote Schuur Hospital and
the University of Cape Town Medical School have contributed. Though
considerable advances have been made in preventing or treating the
complications of heart transplantation, even today a transplant pro-
gramme remains a major undertaking for a hospital team. The acquisition
of a sufficient number of donor hearts, the maintenance of viability of
those hearts, and the prevention, diagnosis and treatment of acute and
chronic rejection and infection remain major challenges to those caring
for patients undergoing this operation. A transplant programme draws
into it medical, surgical, nursing and paramedical staff from all
quarters of the hospital and medical school, and requires sustained
interest and dedication if patients are to be brought successfully
through the procedure. If relevant experimental research is also to be
carried out at such a centre, which in my opinion is essential, then an
even greater number of highly skilled and creative people is required. A
few of the authors of this book have been involved with the Groote
Schuur heart transplant programme since its inception in December 1967
with the operation on Louis Washkansky. I am sure that none of them (nor
I) had any idea of the public interest this operation would attract.