This book examines what is known about the molecular biology of multiple
endocrine neoplasia, type 2 (MEN2). Mutations and alterations in gene
expressions and signal transduction are placed in the context of their
effects on the biology of the thyroid and adrenal cells which generate
cancers in MEN2. Thus, this volume addresses the ret mutations, the
effects these mutations may have on signal transduction, and
developmental and neurobiological aspects of the cells affected of MEN2,
and provides the basic researcher - in genetics, signal transduction,
cell transformation, developmental or neurobiology - with a better
understanding of how the knowledge generated by each of these fields
intercalates within the overall biology of MEN2.