Xinfeng Zhao

(Author)

G Protein-Coupled Receptors: Immobilization and Applications in Drug Discovery (2023)Paperback - 2023, 21 February 2023

G Protein-Coupled Receptors: Immobilization and Applications in Drug Discovery (2023)
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Part of Series
Springerbriefs in Molecular Science
Print Length
91 pages
Language
English
Publisher
Springer
Date Published
21 Feb 2023
ISBN-10
9819900778
ISBN-13
9789819900770

Description

This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the "post-structural biology" era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical reactions by using their high specificity and robust reactivity in the complex system, such as site-specific conjugation by covalent recognition between enzymes and their substrates. With the perspective of protein-drug interactions, this book also reviews the applications of protein immobilization, with an emphasis on G protein-coupled receptors, in drug discovery and protein-ligand interaction analysis. In addition, the merits, opportunities and disadvantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other related field, as well as teachers of relevant majors in colleges and universities.

Product Details

Authors:
Xinfeng ZhaoQian LiJing WangQi LiangJia Quan
Book Edition:
2023
Book Format:
Paperback
Country of Origin:
NL
Date Published:
21 February 2023
Dimensions:
23.39 x 15.6 x 0.56 cm
ISBN-10:
9819900778
ISBN-13:
9789819900770
Language:
English
Location:
Singapore
Pages:
91
Publisher:
Weight:
158.76 gm

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