Even high-speed supercomputers cannot easily convert traditional
two-dimensional databases from chemical topology into the
three-dimensional ones demanded by today's chemists, particularly those
working in drug design. This fascinating volume resolves this problem by
positing mathematical and topological models which greatly expand the
capabilities of chemical graph theory. The authors examine QSAR and
molecular similarity studies, the relationship between the sequence of
amino acids and the less familiar secondary and tertiary protein
structures, and new topological methods.