This book reviews important findings from the Extremely Low Gestational
Age Newborn Study (ELGAN), the largest cohort study ever completed
involving individuals born extremely prematurely. With a focus on pre-,
peri-, and post-natal inflammation, this study identified potentially
modifiable risk factors and pathways antecedent to a broad range of
neurodevelopmental impairments, as well as asthma and obesity, during
middle childhood. These findings will be of interest to both practicing
neonatologists and developmental paediatricians, as well as researchers
interested in the prevention of adverse child health outcomes and
promotion of positive health among individuals born extremely preterm.
- The only book to summarise findings from the Extremely Low Gestational
Age Newborn Study, the largest and most comprehensive cohort study
ever conducted of this high-risk group.
- A comprehensive 'one-stop-shopping' resource.
- A broad range of neurodevelopmental outcomes are included, as well as
the relationship of these outcomes to pre-, peri-, and post-natal risk
factors. A focus of the study was perinatal inflammation, and the
methods used to evaluate inflammation are the most comprehensive ever
undertaken in an epidemiologic study of individuals born extremely
preterm.
- The results of the ELGAN study will help Make a difference in the care
and outcome of children born very early and make an important
contribution to preventing learning and behavioural problems in
children.