Present study aims to the evaluation of the microbial quality of Yamuna
water at Agra region. Water samples were collected from different
location of Agra city, during the period from March 2010 to June 2010.
The water sample are analysed for physiochemical parameter such as
temperature, TDS, turbidity and pH and were screened for contamination
of Klebsiella and assessed for multiple drug resistance, which are
commonly encountered in the water of Yamuna river. The results of
physicochemical parameters showed that the temperature values varied
from 18.9 - 37.4°C and TDS from 200 - 700 mg/ml, whereas the turbidity
varied from 4 - 52 NTU and pH values from 6.1 to 9.2. The
bacteriological analysis showed that TVBCs ranged from 8.8 x 10 to 152 x
10 cfu/ml at 37°C. The cumulative resistance of the Klebsiella isolates
to the antibiotics ranged from 53.3 - 80%. Among the 8 antibiotics
tested, one patterns of multiple resistance was found and number of
antibiotics was five. The result indicated that persistent use of
antibiotics against human diseases and other life forms may pollute the
Yamuna water and their impact on developing antibiotic resistant
Klebsiella may become a serious threat