Epigenetics is a rapidly expanding field in medical and biological
research which concerns heritable traits that are not attributable to
changes in the DNA sequence. Epigenetic mechanisms play key roles in
many biological processes, and it has become clear that their disruption
can gives rise to diverse pathologies in humans. Edited by preeminent
experts, Sophie Rousseaux and Saadi Khochbin, this volume in the
'Epigenetics and Human Health' series discusses the role of epigenetics
in human reproduction. The book presents epigenetic transitions that are
important at defined stages of gametogenesis and during meiosis.
Finally, the authors discusses how in vitro manipulation and culture in
assisted reproduction can epigenetically perturb germ cells, and how
this can trigger disease phenotypes in the next generation. Conceived
towards advanced students, medical professionals and research
scientists, this is the first comprehensive textbook on this topic that
will serve as a valuable reference during the years to come.