High fluorides ingestion through drinking water affects the body system
of human being. No treatment was successful in the children with
fluorosis. This study reports successful treatment of fluorosis in
children and possible preventive measures. Double blind cross sectional
clinical study was conducted on 200 children consuming water containing
2.4, 4.6, 5.6 and 13.5 mg/l of fluoride of various age groups. A note
was made for clinical, radiological and dental fluorosis. Biochemical
estimations were made for serum calcium, serum and urinary fluoride and
serum parathyroid hormone. It was observed that high Fluoride ingestion
causes increased parathyroid hormone secretion, which is responsible for
maintaining serum calcium levels and leading to manifestations of
fluorosis. The supplementation of a therapeutic regime of Calcium,
Vitamin C and Vitamin D in these children reported reversal of
fluorosis, indicating that this therapy can be employed successfully in
children suffering from fluorosis. For prevention, Intake of fluoride
can be reduced by the use of simple defluoridation technique, reducing
intake of fluoride rich items and use of food rich in calcium, Vitamin C
and protein.