Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes
termed Electron Spin Resonance spectroscopy - has manifold potential
uses in biochemistry and medicine. The paramount importance of EPR
spectroscopy applied to biological tissues and fluids is that it
identifies the changes in redox processes that contribute to disease.
EPR spectroscopy has come a long way from its original use to detect
malignant tumors. For example, the development and later refinement of
methods of low-temperature registration of biological tissues widened
the scope of EPR spectroscopy. Innovations made possible by the
introduction of spin labels, probes, and traps made EPR spectroscopy
ever more applicable to biochemistry and medicine, to the point where
in vivo studies are being carefully considered.
This comprehensive book discusses spectra of many tissues and bodily
fluids, and the quantitative nature of paramagnetic centers in both
normal individuals and patients suffering from a variety of diseases.
Special attention is given to the EPR examination of bio-molecules, such
as enzymes, polypeptides, vitamins, lipids, hydrocarbons, etc., which
play an essential role in human activity.
This book will be of great interest to physicians specializing in many
different areas. Similarly, biologists, biochemists, biophysicists, and
chemists will find this book very useful. It has also been written so
that it may be used as a textbook at graduate level.