This volume comprises the proceedings of a NATO Advanced Study Institute
(ASI) held at Geilo, Norway, 11-21 April 2005, the eighteenth ASI in a
series held every two years since 1971. The objective of this ASI was to
identify and discuss areas where synergism between modern physics and
biology may be most fruitfully applied to the study of bioprocesses for
molecular recognition, and of networks for converting molecular
reactions into usable signals and appropriate responses. Many fields of
research are confronted with networks. Genetic and metabolic networks
describe how proteins, substrates and genes interact in a cell; social
networks quantify the interactions between people in the society; the
Internet is a complex web of computers; ecological systems are best
described as a web of species. In many cases, the interacting networks
manifest so-called emergent properties that are not possessed by any of
the individual components. This means that the detailed knowledge of the
components is insufficient to describe the whole system. Recent work has
indicated that networks in nature have so-called scale-free
characteristics, and the associated dynamic network modelling shows
unexpected results such as an amazing robustness against accidental
failures, a property that is rooted in their inhomogeneous topology.
Understanding these phenomena and turning them to use in chemical and
biological threat detection and response will require exploring a wide
range of network structures as well.