A comprehensive review of the science of drug testing in all its
aspects, placing emphasis on technologies that use body fluids other
than urine for determining the presence of drugs of abuse. The authors
discuss the various body fluid specimens suitable for testing for
illicit drugs-particularly saliva, sweat, and hair-describe the
structural and manufacturing aspects of on-site testing devices based on
lateral flow immunoassay, and detail the pitfalls of using these
specimens. They also discuss in detail the problem of sample
adulteration and its detection. Since oral fluid has the best potential
of succeeding urine as the next matrix of choice for drug detection,
four popular saliva testing devices are examined: Intercept(R), the
Drager Drug Test(R), Oratect(R), and Drugwipe. Political, social, and
legal issues are also considered in articles on privacy, the use of drug
testing in courts, and the problem of sample adulteration.