In recent years both doctors and patients have become increasingly aware
that many essential drugs may induce unfortunate side-effects in
susceptible individuals. The kidney is the principal route of excretion
for many of these substances and may as a result become involved in
pathological processes. Developments in haemodialysis and haemo-
perfusion may be of value in increasing the rate of excretion of
potentially toxic substances but it is essential that the advantages and
disadvantages of these techniques are fully appreciated by all with an
interest in clinical practice. This book details the recent advances in
understanding of analgesic nephropathy, interstitial nephritis,
elimination of poisons and drug monitoring. Each chapter has been
written by a recognized expert in the field and provides information of
relevance and practical import- ance to the average clinician. The
developments of the last decade have emphasized that drug toxicity is a
subject on which all clinicians, but perhaps especially nephrologists,
should be fully informed. ABOUT TH E EDITOR Professor Graeme R. D. Catto
is Professor in Medicine and Thera- peutics at the University of
Aberdeen and Honorary Consultant Phy- sician/Nephrologist to the
Grampian Health Board. His current interest in transplant immunology was
stimulated as a Harkness Fellow at Harvard Medicial School and the Peter
Bent Brighton Hospital, Boston, USA. He is a member of many medical
societies including the Association of Physicians of Great Britain and
Ireland, the Renal Association and the Transplantation Society.