Resistance to treatment represents the final common outcome for far too
many patients with cancer. Even our most promising new drugs fall victim
to drug resistance. Hormones and newer biological therapies, though safe
and active, also lose their activity over time.
In this volume of Drug Resistance, leading investigators in the field
have reviewed the most basic mechanisms of drug resistance, and have
proposed ways to modulate resistance. This comprehensive volume should
be of value for basic and clinical scientists who wish to delve more
deeply into this intriguing problem in the laboratory and devastating
problem in the clinic.