Diarrhea a leading cause of illness and death in children in developing
countries may lead to the cause of dehydration resulting from loss of
water and electrolytes and lack of absorption of nutrients due to
inflammatory bowel. A total of forty (40) blood samples were collected
from normal and diarrheal children from Allied and Civil Hospital,
Faisalabad belong to middle socio-economic class. Blood samples were
collected with and without anticoagulant from each individual for
separation of serum which was presented at -2°C. Serum biochemicals,
hormones and health markers were estimated in triplicate while using
standard procedures of analysis. A significant high concentration of
LDL, ALT, homocysteine, total oxidant status, K and Mg while serum
triglyceride, total proteins, albumin, globulin, T3, T4, total
antioxidant status, Na, Ca, Zn and Cu were significantly low in patients
with diarrhea. Diarrhea patients have shown a significant increase in
DNA damage. In addition, DNA damage has shown a positive correlation
with glucose, LDL and with potassium while negative correlation was
observed with total proteins, thyroxine, total antioxidant status,
sodium and calcium
