Indiscriminate use of anthelmintics has led to the problem of
anthelmintic resistance in most developing countries. This burning
problem has made goat farming uneconomical in India. This book describes
the detection of benzimidazole resistance in Haemonchus contortus in
goats in Central India. Faecal egg count reduction test revealed that H.
contortus is resistant to fenbendazole which was further confirmed by
Egg hatch assay. The prevalence of homozygous resistant genotype and
resistant allele at 200 codon of β-tubulin Isotype I gene was 62% and
74%, respectively. An effort for the management of anthelmintic
resistance was made by using herbal anthelmintics as well as commonly
used anthelmintics with different mechanism of action like closantel and
doramectin. The benzimidazole resistant nematodes were found fully
susceptible to both these synthetic anthelmintics. Aqueous leaf extracts
of Azadirachta indica, Annona squamosa and Nicotiana tabacum were also
tried in vivo against benzimidazole resistant gastrointestinal
naematodes but were found not much effective in controlling these
parasites. This book is therefore very useful for researchers,
veterinarians and goat farmers.