Nearly three thousand papers and patents are dedicated to the actual or
potential uses of cyclodextrins in pharmacy and pharmaceutical
formulations. This is the first book written for pharmacists and
pharmaceutical technologists which not only critically summarizes the
enormous amount of literature available, but which can be used as a
handbook when looking for solutions to practical problems.
The fundamentals -- chemistry of cyclodextrins and their derivatives --
their physical and chemical properties are condensed to the most
relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption,
metabolism and toxicological properties of cyclodextrins. Chapter 4
explains the formulation, structure, composition and advantageous
effects of the cyclodextrin inclusion complexes. Chapter 5 describes the
methods for preparation and characterization of drug/cyclodextrin
complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics,
biopharmaceutical and technological aspects of drug/CD complexes.
Chapter 8 treats the application and effects of cyclodextrins in various
drug formulations. The Appendix comprises a collection of recipes for
any type of drug formulation.
This book is aimed at those who use cyclodextrins in drug formulations,
to improve the properties of existing drug formulations, or who want to
prepare quite new formulations.